Metachronous Sarcoma: A Case of Pleomorphic Leiomyosarcoma in a Patient with a History of Fibrosarcoma

Abstract

Metachronous cancers were defined as those that were detected after an interval of more than 6 months. The instance of two histologically distinct sarcomas in one patient is very unusual. A 42-year-old woman presented for evaluation of a painless mass in her right axilla area. She gave a history of operation 8 years ago for treating a fibrosarcoma on her right upper arm at local clinic. Eight years ago, the lesion was widely excised. Magnetic resonance imaging revealed a new generated tumor at her right axilla. After a wide surgical resection, we performed anterolateral thigh free flap for cover the defect. Second neoplasm is leiomyosarcoma. These two neoplasms are 2 histologically distinct tumors. There is no report of a case of metachronous soft tissue sarcoma both pleomorphic leiomyosarcoma and fibrosarcoma in upper extremity within one person. We emphasize the importance of considering the possibility of metachronous sarcoma.