스펙트럼 영역 빛간섭단층촬영기를 이용한 근시 정도에 따른 황반 구조의 정량적 분석
- Alternative Title
- Use of Spectral-Domain Optical Coherence Tomography to Analyze Macular Thickness According to Refractive Error
- Abstract
- PURPOSE: To investigate the correlation of macular retinal thickness and refractive error using spectral-domain optical coherence tomography (SD-OCT). METHODS: A total of 120 eyes with no posterior abnormalities were enrolled in the present study. Subjects were divided into 3 groups based on their spherical equivalent. Visual acuity, refraction, slit lamp examination, tonometry and fundus examination were performed. Retinal thickness between the RPE and IS/OS junction was measured at the fovea, 1 mm (inner ring) and 2 mm (outer ring) superiorly, inferiorly, nasally and temporally using SD-OCT. Overall average thickness, average foveal thickness, and the inner and outer ring macular thickness were measured. RESULTS: The average foveal thickness was significantly greater in the high myopic eyes than in the low to moderate myopic and emmetropic eyes (p = 0.001). However, the RPE-IS/OS junction thickness of the foveola and the outer macular thickness were significantly lower (p = 0.001, p = 0.002) in the high myopic eyes. There was a weak, but significant negative correlation between refractive error and average foveal thickness (r = -0.38, p = 0.001). A positive correlation was found between refractive error and the RPE-IS/OS junction thickness (r = 0.40, p = 0.001). CONCLUSIONS: Macular retinal thickness is related to refractive error in normal subjects. Effects of eyeball elongation are more apparent in high myopic eyes than in low to moderate myopic eyes. A significant decline in the RPE-IS/OS junction thickness suggests the photoreceptor outer segments in the foveola are damaged in high myopic eyes.
- All Author(s)
- S. H. Kim
; J. Y. Park
; T. K. Park
; Y. H. Ohn
- Issued Date
- 2011
- Type
- Article
- Keyword
- Macula; Macular thickness; Myopia; Refractive error; Spectral-domain optical coherence tomography
- Publisher
- 대한안과학회
- ISSN
- 0378-6471
; 2092-9374
- Citation Title
- 대한안과학회지
Journal of the Korean Opthalmological Society
- Citation Volume
- 52
- Citation Number
- 11
- Citation Start Page
- 1286
- Citation End Page
- 1295
- Language(ISO)
- kor
- DOI
- 10.3341/jkos.2011.52.11.1286
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/971
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