이차성 유아구성 외투세포림프종 1예
- Alternative Title
- Blastoid Mantle Cell Lymphoma: A Case Report
- Abstract
- Mantle cell lymphoma (MCL) is a low-grade malignant lymphoma derived from a subset of B-cells localized in the mantle zone of the lymphoid follicle. MCL commonly involves extranodal sites, usually as a manifestation of disseminated disease. The immunophenotype of MCL is characterized as CD20+, CD5+ and Cyclin D1+. Blastoid mantle cell lymphoma (BV-MCL) is a rare variant and has a more aggressive clinical course. In the blastoid variant,the genetic profile is often more complex and includes tetraploid chromosomes, CCND1 amplification, a higher incidence of p53 gene mutations, and p16(INK4a) deletions. We report a case of a 62-year-old male patient who presented with erythematous subcutaneous nodules on the lower back. He had been treated for BV-MCL of the testis which had occurred 1 year ago. The analysis of histopathological and immunohistochemical examinations of the skin lesions also revealed a BV-MCL.
- All Author(s)
- 신정웅
; 양정훈
; 이성열
; 이종석
; 박영립
; 조문균
; 조현득
- Issued Date
- 2010
- Type
- Article
- Keyword
- Blastoid; Mantle cell lymphoma; Skin
- Publisher
- 대한피부과학회
- ISSN
- 0494-4739
- Citation Title
- 대한피부과학회지
Korean Journal of Dermatology
- Citation Volume
- 48
- Citation Number
- 8
- Citation Start Page
- 684
- Citation End Page
- 688
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/521
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