Impact of health care-associated community-onset cellulitis in Korea: a multicenter study
- Abstract
- We conducted a multicenter study to determine the clinical and microbiological characteristics of health care-associated (HCA) cellulitis in Korea. We retrospectively reviewed the medical records of patients who had been diagnosed with community-onset cellulitis. Of the 2208 cellulitis patients, 232 (10.5%) had HCA cellulitis, 1243 (56.3%) patients were hospitalized, and 15 (0.7%) died in hospital. Compared with community-acquired (CA) cellulitis, patients with HCA cellulitis were older and more frequently presented with comorbidity and septic shock. A total of 355 microorganisms were isolated from 314 patients (14.2%). Staphylococcus aureus (134 isolates) was the most common organism, followed by Streptococcus spp. (86 isolates) and Gram-negative fermenters (58 isolates). Methicillin-resistant S. aureus (MRSA) accounted for 29.1% (39/134) of S. aureus infections. None of the Gram-negative fermenters were resistant to carbapenem. The antibiotic susceptibility pattern of isolated microorganisms was not different between HCA and CA cellulitis. In patients with HCA cellulitis, S. aureus (11.2% [26/232] vs. 5.5% [108/1976], p = 0.001), including MRSA (4.3% [10/232] vs. 1.5% [29/1976], p = 0.003) and Gram-negative fermenters (6.0% [14/232] vs. 2.3% [44/1976], p = 0.002), were more common causative organisms than in CA-cellulitis patients. Age ≥ 65years, septic shock, and HCA infection were statistically significant factors associated with in-hospital mortality.
- All Author(s)
- S. Y. Park
; T. Kim
; S. H. Choi
; J. Jung
; S. N. Yu
; H. L. Hong
; Y. K. Kim
; E. H. Song
; K. H. Park
; O. H. Cho
; Y. G. Kwak
- Intsitutional Author(s)
- 유시내
- Issued Date
- 2019
- Type
- Article
- Keyword
- Cellulitis; Health care–associated infection; Staphylococcus aureus
- Publisher
- European Society of Clinical Microbiology
- ISSN
- 0934-9723
- Citation Title
- European Journal of Clinical Microbiology & Infectious Diseases
- Citation Volume
- 38
- Citation Number
- 3
- Citation Start Page
- 545
- Citation End Page
- 552
- Language(ISO)
- eng
- DOI
- 10.1007/s10096-018-03456-0
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2635
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