Comparison of MOG and AQP4 antibody seroprevalence in Korean adults with inflammatory demyelinating CNS diseases
- Abstract
- We aimed to compare seroprevalence of anti-myelin oligodendrocyte glycoprotein (MOG) and anti-aquaporin-4 (AQP4) antibodies in Korean adults with inflammatory demyelinating diseases (IDDs) of the central nervous system (CNS), based on a multicenter nationwide database. Sera were analyzed using a live cell-based assay for MOG and AQP4 antibodies. Of 586 Korean adults with IDDs of the CNS, 36 (6.1%) and 185 (31.6%) tested positive for MOG and AQP4 antibodies, respectively. No participant showed double positivity. Seroprevalence of MOG antibodies was about five times lower than that of AQP4 antibodies in a large cohort of Korean adults with IDDs of the CNS.
- All Author(s)
- J. W. Hyun
; H. L. Lee
; W. K. Jeong
; H. J. Lee
; J. H. Shin
; J. H. Min
; B. J. Kim
; S. W. Kim
; H. Y. Shin
; J. Oh
; W. Kim
; H. J. Shin
; S. Y. Oh
; H. Kim
; Y. M. Lim
; S. Y. Huh
; E. B. Cho
; T. S. Nam
; S. H. Lee
; S. Y. Kim
; S. Y. Kang
; S. G. Han
; E. H. Sohn
; S. H. Baek
; S. S. Lee
; J. M. Seok
; Y. H. Hong
; S. I. Oh
; J. K. Kim
; K. J. Shin
; O. Kwon
; J. Y. Cho
; J. S. Bae
; Y. Kim
; M. Y. Lee
; S. H. Kim
; H. J. Kim
- Issued Date
- 2021
- Type
- Article
- Keyword
- Aquaporin-4; adult; myelin oligodendrocyte glycoprotein; prevalence
- Publisher
- SAGE Publications
- ISSN
- 1352-4585
; 1477-0970
- Citation Title
- Multiple sclerosis : clinical and laboratory research
- Citation Volume
- 27
- Citation Number
- 6
- Citation Start Page
- 964
- Citation End Page
- 967
- Language(ISO)
- eng
- DOI
- 10.1177/1352458520948213
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2485
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