Efficacy and Safety of Therapeutic Endoscopic Retrograde Cholangiopancreatography in the Elderly Over 80 Years
- Abstract
- BACKGROUND/AIMS: Concern regarding the safety and efficacy of therapeutic endoscopic retrograde cholangiopancreatography (ERCP) in elderly patients is increasing as a result of the aging society. However, there are limited data, especially in the super-aged elderly. This study aimed to evaluate the efficacy and safety of therapeutic ERCP in patients ≥80years of age. METHODS: Patients 80years of age or older (n=312) and younger than 65years (n=312) who underwent therapeutic ERCP from June 2006 to April 2014 were randomly selected and analyzed retrospectively. The main outcome measurements were therapeutic ERCP-related complications and clinical outcomes in the two groups. RESULTS: Choledocholithiasis combined with gallbladder stone was the most common indication for ERCP in both groups. Comorbid diseases (70.5 and 29.8%, p<0.001) and the use of anti-thrombotic drugs (18.6 and 1.6%, p<0.001) were more frequent in the super-aged group. The mean procedure time was longer, and the frequency of second ERCP was more common in the super-aged group. However, the technical success rate (94.9 and 97.4%, p=0.096) and the procedure-related complication rate (4.8 and 5.8%, p=0.592) were not different between the two groups. Post-ERCP pancreatitis occurred in 1.3% of the super-aged group and in 2.9% of the control group (p=0.262). Cardiopulmonary complications occurred in 1.9% of patients in each group (p=1.0). CONCLUSIONS: Therapeutic ERCP is comparable in terms of efficacy and safety between patients ≥80years and those <65years of age, although the elderly group had a higher rate of comorbid diseases and used anti-thrombotic drugs more frequently.
- All Author(s)
- S. J. Han
; T. H. Lee
; B. I. Kang
; H. J. Choi
; Y. N. Lee
; S. W. Cha
; J. H. Moon
; Y. D. Cho
; S. H. Park
; S. J. Kim
- Issued Date
- 2016
- Type
- Article
- Keyword
- Endoscopic retrograde cholangiopancreatography; Elderly; Efficacy; Safety; Complications
- ISSN
- 0163-2116
- Citation Title
- Digestive Diseases and Sciences
- Citation Volume
- 61
- Citation Number
- 7
- Citation Start Page
- 2094
- Citation End Page
- 2101
- Language(ISO)
- eng
- DOI
- 10.1007/s10620-016-4064-y
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2280
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