만성폐쇄성질환 환자에서 정량적 CT 분석: 임상 증상과 폐기능 검사 소견이 일치하는 환자군과 일치하지 않는 환자군의 비교 연구
- Alternative Title
- Quantitative CT Assessment in Chronic Obstructive Pulmonary Disease Patients: Comparison of the Patients with and without Consistent Clinical Symptoms and Pulmonary Function Results
- Abstract
- Purpose
We compared the clinical and quantitative CT measurement parameters between chronic obstructive pulmonary disease (COPD) patients with and without consistent clinical symptoms and pulmonary function results.
Materials and Methods
This study included 60 patients having a clinical diagnosis of COPD, who underwent chest CT scan and pulmonary function tests. These 60 patients were classified into typical and atypical groups, which were further sub-classified into 4 groups, based on their dyspnea score and the result of pulmonary function tests [typical 1: mild dyspnea and pulmonary function impairment (PFI); typical 2: severe dyspnea and PFI; atypical 1: mild dyspnea and severe PFI; atypical 2: severe dyspnea and mild PFI]. Quantitative measurements of the CT data for emphysema, bronchial wall thickness and air-trapping were performed using software analysis. Comparative statistical analysis was performed between the groups.
Results
The CT emphysema index correlated well with the results of the pulmonary functional test (typical 1 vs. atypical 1, p = 0.032), and the bronchial wall area ratio correlated with the dyspnea score (typical 1 vs. atypical 2, p = 0.033). CT air-trapping index also correlated with the results of the pulmonary function test (typical 1 vs. atypical 1, p = 0.012) and dyspnea score (typical 1 vs. atypical 2, p = 0.000), and was found to be the most significant parameter between the typical and atypical groups.
Conclusion
Quantitative CT measurements for emphysema and airways correlated well with the dyspnea score and pulmonary function results in patients with COPD. Air-trapping was the most significant parameter between the typical vs. atypical group of COPD patients.
- All Author(s)
- B. Nam
; J. H. Hwang
; Y. M. Lee
; J. S. Park
; S. S. Jou
; Y. Kim
- Issued Date
- 2015
- Type
- Article
- Keyword
- Chronic Obstructive Pulmonary Disease; Emphysema; Air-Trapping; CT Quantification
- Publisher
- 대한영상의학회
- ISSN
- 0301-2867
; 1738-2637
; 2288-2928
; 2951-0805
- Citation Title
- 대한영상의학회지
Journal of the Korean Society of Radiology
- Citation Volume
- 73
- Citation Number
- 3
- Citation Start Page
- 147
- Citation End Page
- 157
- Language(ISO)
- kor
- DOI
- 10.3348/jksr.2015.73.3.147
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/1667
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