게르마늄강화효모가 혈청지질 및 면역세포변화에 미치는 영향
- Alternative Title
- Effects of Germanium-fortified Yeast on the Serum Lipids and Immune Cell Subset
- Abstract
- This study was established to investigate the effect of germanium-fortified yeasts on the serum lipid composition and immune system of human body. All 50 subjects with the age range of $50{\sim}75$ were entered in this clinical trial for 6 months. The effects were determined by the proliferative responses of immune-mediated cells, T-cell, B-cell and NK-cell during daily supplementation with/without germanium-fortified yeast. The results of hematology and blood chemistry didn't show any significant differences during administration periods. Serum lipid compositions also didn't show any significant differences during administration periods except triglyceride (TG) and VLDL-cholesterol. TG and VLDL-cholesterol levels were increased significantly by the consumption of germanium-fortified yeast (p<0.05). Immune mediated T-celt and NK-cell didn't increased in both control and test group supplemented with germanium fortified yeast, while B-cell increased in the germanium fortified yeast group after 8 week (p<0.05). Also $TNF-{\alpha}$ increased in the group of germanium fortified yeast after 8 week (p<0.05) but not in the control group. From the above results, germanium fortified yeast is expected to be useful on the improvement of the cellular immune response and protection of organs from various chronic diseases.
- All Author(s)
- 이성희
; 오선우
; 노숙령
; 이복희
; 이현주
; 진동규
- Issued Date
- 2006
- Type
- Article
- Keyword
- serum lipid; immune cell; germanium-fortified yeast; clinical trial
- ISSN
- 0253-3154
; 1226-3311
; 2288-5978
- Citation Title
- 한국식품영양과학회지
Journal of the Korean Society of Food Science and Nutrition
- Citation Volume
- 35
- Citation Number
- 6
- Citation Start Page
- 683
- Citation End Page
- 689
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr//handle/2022.oak/386
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