가토안에서 전방내 트리암시놀론 주입술이 각막에 미치는 영향
- Alternative Title
- The Effect of Intracameral Triamcinolone Acetonide Injection on the Cornea in Rabbits
- Abstract
- Purpose: To evaluate the safety and effects of intracameral triamcinolone acetonide injection in rabbit corneas. Methods: Triamcinolone acetonide in the amounts of 0.5, 1, and 2 mg was injected into the anterior chamber of rabbit eyes, and intraocular pressure, corneal thickness, and endothelial cell counts were evaluated on days 1, 3, 7, 14, and 28. Twenty-eight days after triamcinolone acetonide injection, the eyes were enucleated and examined after TUNEL staining. Results: No statistically significant differences were found among control, 0.5, and 1 mg triamcinolone- injected eyes in central corneal thickness, endothelial cell density, pleomorphism, and polymegathism. There was no difference between 2 mg triamcinolone-injected eyes and control eyes for corneal thickness and cell density, but there were statistically significant differences between these two groups for pleomorphism (p<0.05) and polymegathism (p<0.05). Conclusions: The results of this study suggested that intracameral injections of 0.5~1 mg of triamcinolone acetonide are beneficial and cause no toxic effects on corneas.
- All Author(s)
- 박주연
; 김훈동
; 최경식
- Issued Date
- 2008
- Type
- Article
- Keyword
- Cornea; Intracameral triamcinolone acetonide injection
- ISSN
- 0378-6471
; 2092-9374
- Citation Title
- The Effect of Intracameral Triamcinolone Acetonide Injection on the Cornea in Rabbits
- Citation Volume
- 49
- Citation Number
- 4
- Citation Start Page
- 634
- Citation End Page
- 640
- Language(ISO)
- kor
- DOI
- 10.3341/jkos.2008.49.4.634
- URI
- http://schca-ir.schmc.ac.kr//handle/2022.oak/380
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