A comparison of oxycodone and fentanyl in intravenous patient-controlled analgesia after laparoscopic hysterectomy
- Abstract
- Background: We planned to compare the effect of intravenous oxycodone and fentanyl on post-operative pain after laparoscopic hysterectomy.
Methods: We examined 60 patients were randomized to postoperative pain treatment with either oxycodone (n = 30, Group O) or fentanyl (n = 30, Group F). The patients received 10 mg oxycodone/100 µg fentanyl with ketorolac 30 mg before the end of anesthesia and then continued with patient-controlled analgesia for 48 h postoperatively.
Results: The accumulated oxycodone consumption was less than fentanyl during 8, 24 and 48 h postoperatively. Numeric rating score of Group O showed significantly lower than that of Group F during 30 min, 2, 4, 8 and 24 h postoperatively. The incidences of adverse reactions were similar in the two groups, though the incidence of nausea was higher in the Group O during the 24 and 48 h postoperative period.
Conclusions: Oxycodone IV-PCA was more advantageous than fentanyl IV-PCA for laparoscopic hysterectomy in view of accumulated oxycodone consumption, pain control and cost beneficial effect. However, patient satisfaction was not good in the group O compared to group F.
- All Author(s)
- N.-S. Kim
; K. S. Kang
; S. H. Yoo
; J. H. Chung
; J.-W. Chung
; Y. Seo
; H.-S. Chung
; H.-R. Jeon
; H. Y. Gong
; H.-Y. Lee
; S.-T. Mun
- Issued Date
- 2015
- Type
- Article
- Keyword
- Fentanyl, Oxycodone, Postoperative pain
- Publisher
- 대한마취과학회
- ISSN
- 2005-6419
; 2005-7563
- Citation Title
- 대한마취과학회지
Korean journal of anesthesiology
- Citation Volume
- 68
- Citation Number
- 3
- Citation Start Page
- 261
- Citation End Page
- 266
- Language(ISO)
- eng
- DOI
- 10.4097/kjae.2015.68.3.261
- URI
- http://schca-ir.schmc.ac.kr//handle/2022.oak/294
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