메틸렌블루에 반응하지 않는 메트헤모글로빈혈증 1례
- Alternative Title
- A Fatal Case of Methylene Blue Threatment Failure in Methemoglobinemia
- Abstract
- Acute toxic methemoglobinemia is an infrequent complication of the use of various drugs. Severe methemoglobinemia is very often fatal. Methylene blue is an effective drug in the treatment of methemoglobinemia patients. However, failure to respond to methylene blue has been described in patients with sulfhemoglobinemia, chlorate poisoning, and glucose-6-phosphate dehydrogenase deficiency. It is even possible that hemolysis may occur due to methylene blue treatment itself. We encountered a case of a 71-year-old woman who developed methemoglobinemia caused by alprazolam intoxication. She presented with hemolytic anemia and did not respond to methylene blue. In spite of concerted N-acetylcysteine therapy, the hemolytic anemia became aggravated and the patient died eleven days after intoxication.
- All Author(s)
- 심지예
; 서연석
; 양종오
; 이은영
; 홍세용
; 길효욱
- Issued Date
- 2006
- Type
- Article
- Keyword
- Methemoglobinemia; Hemolytic anemia; Methylene blue
- Publisher
- 대한임상독성학회
- ISSN
- 1738-1320
; 2508-6332
- Citation Title
- 대한임상독성학회지
Journal of the Korean Society of Clinical Toxicology
- Citation Volume
- 4
- Citation Number
- 2
- Citation Start Page
- 151
- Citation End Page
- 154
- Language(ISO)
- kor
- URI
- http://schca-ir.schmc.ac.kr//handle/2022.oak/449
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